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Promontory on the Ionian coast between Ephesus and Miletus, facing the island of Samos (area 6).
Mycale was also the name of a summit on that promontory, on which a confederacy of twelve Ionian cities founded in Asia Minor by Ionians coming from Attica and what later became Achaia in northern Peloponnese, collectively called the Paniones (etymologically, "all the Ionians pan Iônes"), had erected a sanctuary to Poseidon called the Panionion where they celebrated a yearly festival called Panionia. The twelve cities of the Ionian confederacy included, from south to north, the Carian cities of Miletus (the leading city of Ionia), Myous and Priene, the Lydian cities of Ephesus, Colophon, Lebedus, Teos, Clazomenæ and Phocæa, plus Samos and Chios on the islands of the same names, and Erythræus on the mainland facing Chios (Herodotus' Histories, I, 142-148).
Cape Mycale was, in 479, the site of a naval victory of a Greek fleet over a Persian fleet, which, after the victories of Salamis and Platæa, marked the end of the first phase of the second Persian War and of Persian incursions on Greeek mainand.